https://doi.org/10.4081/acbr.2021.139

Pattern of lipid profile in patients attending metabolic clinic in Oghara, Delta State, Nigeria

Vol. 2 No. 1 (2021)
Submitted: 5 March 2021
Accepted: 2 April 2021
Published: 20 April 2021
Dyslipidemia, hypercholesterolemia, total cholesterol, HDL, LDL, antherogenic ratio, Castelli ratios
Abstract Views: 1206
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Authors

Voke Peter Orugbo
drorugbopeter@gmail.com
https://orcid.org/0000-0001-6391-5732
Department of Chemical Pathology, Delta State University, Abraka, Delta State, Nigeria.

Owing to its high prevalence, dyslipidemia is rapidly becoming a major public heart issue worldwide, and especially in Nigeria. Although it is a preventable significant risk factor for coronary heart disease, it is a common leading cause of death in Nigeria. The study therefore investigated the lipid profiles of patients attending Metabolic Clinic at the Delta State University Teaching Hospital (DELSUTH). A total of 713 participants were recruited for the study. Blood samples (5mls) were collected via venipuncture from each of the participants and distributed into tubes containing EDTA and fluoride oxalate. A spectrophotometer was used to conduct the lipid analysis, and the normal operating assay protocol was followed. Results showed total cholesterol in the male (194.6 mg/dL) were generally lower than in the females, particularly for participants below the age of 40. However, as the ages progressed (that is, above 40 years), total cholesterol in males became higher than those in the females. Antherogenic ratio as well as antherogenic index of plasma were higher in the female gender at ages below 40 years. The study showed that the risk of hypercholesterolemia may be higher within the active age period of 30-60 years. As seen in the current study, plasma lipid levels change drastically by sexual development or maturity, and the trends vary by age and sex. The study also significantly demonstrated the elevated lipids levels in younger women in the study population than older men. When assessing screening and diagnostic criteria for classifying individuals with elevated blood lipid levels, pubertal or sexual growth may be taken into account.

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How to Cite

Orugbo, V. P. (2021). Pattern of lipid profile in patients attending metabolic clinic in Oghara, Delta State, Nigeria. Annals of Clinical and Biomedical Research, 2(1). https://doi.org/10.4081/acbr.2021.139

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