https://doi.org/10.4081/acbr.2022.164

Blood group and its correlation with cardiovascular risk factors: A community survey

Vol. 3 No. 1 (2022)
Submitted: 14 October 2021
Accepted: 11 February 2022
Published: 8 March 2022
Blood group, rhesus, left ventricular hypertrophy, triglycerides, pulse pressure, systolic blood pressure
Abstract Views: 956
PDF: 186
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Authors

Opeyemi O. Oni
oniopeyemi64@gmail.com
https://orcid.org/0000-0002-2790-9834
Department of Medicine, Bowen University, Iwo, Nigeria.
Patience O. Akinwusi
Department of Medicine, Osun State University, Osogbo, Nigeria.
Kehinde Joyce Olufemi-Aworinde
Department of Haematology and Blood transfusion, Bowen University, Iwo, Nigeria.
Abiona O. Odeyemi
https://orcid.org/0000-0002-1670-7321
Department of Medicine, Bowen University, Iwo, Nigeria.
Idowu Ajibola
Department of Community Medicine, Bowen University, Iwo, Nigeria.
Oluwaseyi K. Israel
Department of Community Medicine, Bowen University, Iwo, Nigeria.
Gbenga M. Israel
Department of Medicine, Bowen University, Iwo, Nigeria.
Oluwabukola Ala
https://orcid.org/0000-0003-3227-4121
Department of Medicine, Bowen University, Iwo, Nigeria.
Joel O. Akande
Department of Chemical Pathology, Bowen University, Iwo, Nigeria.
Ayodele O. Aremu
Department of Community Medicine, Bowen University, Iwo, Nigeria.
Adewumi Durodola
https://orcid.org/0000-0002-1156-9177
Department of Family Medicine, Bowen University, Iwo, Nigeria.
James I. Owolabi
https://orcid.org/0000-0003-1372-203X
Department of Surgery, Bowen University, Iwo, Nigeria.

Cardiovascular disease is a leading cause of morbidity and mortality globally. Non-O blood groups have been shown to confer a high risk of coronary heart disease. There is paucity of data on the relationship between blood group and left ventricular hypertrophy, among other cardiovascular risk factors. A community-based study was done to evaluate the blood groups and their associations with conventional cardiovascular risk factors in Ejigbo. Anthropometry, blood pressure and other clinical variables were measured. Blood samples were taken for biochemical analysis for blood group typing, serum cholesterol and triglyceride assay. A 12- lead electrocardiogram was performed. The analysis was done using SPSS version 20 to determine possible relationships between the variables. Two hundred and six cases were recruited and analyzed. The prevalence of the various groups was as follows: A - 23%; B-31.4%; AB-4.4%; O-41.2%; rhesus-positive-92.7% and rhesus-negative-7.3%. Blood group B had similar systolic blood pressure (136.0±23.9 vs 137.3±22.3; p=0.726), higher Sokolow- Lyon voltage sum (3.3±1.1 vs 2.9±0.9; p=0.025) and serum triglycerides [14(21.9%) vs7(8.4%), p=0.021] than those with blood group O. Those with Rhesus Positive status had longer PR interval (169.3±25.4 vs 154.2±19.1; p value=0.055) and QRS duration (83.8±12.8 vs 78.4±7.6; p value=0.043) than those with Rhesus negative blood groups. Binary logistic regression revealed blood group B as an independent determinant of left ventricular hypertrophy( LVH) (OR: 3.028; p=0.012; 95% CI:1.275-7.192). Blood group B is a determinant of LVH. Rhesus positive status is associated with delayed electrical conduction through the myocardium.

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How to Cite

Oni, O. O., Akinwusi, P. O., Olufemi-Aworinde, K. J., Odeyemi, A. O., Ajibola, I., Israel, O. K., … Owolabi, J. I. (2022). Blood group and its correlation with cardiovascular risk factors: A community survey. Annals of Clinical and Biomedical Research, 3(1). https://doi.org/10.4081/acbr.2022.164

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