Outcome of management of neurosurgical patients in the intensive care unit: An early clinical audit of a single institution from a developing country

Submitted: 10 June 2020
Accepted: 22 January 2021
Published: 22 February 2021
Abstract Views: 2096
PDF: 187
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Care of neurosurgical patients in the Intensive Care Unit (ICU) has been evolving in recent times. This included fast growing new techniques in neuromonitoring, neuroimaging and enhanced therapeutic tools. The pace of evolution has not been replicated in resource-constrained setting such as in Nigeria, despite overwhelming evidence of its benefit to neurological patients. Patients’ outcome, including death, in the ICU is a reflection of quality of care assessed during the hospitalization process; as many neurosurgical patients require ICU bed in the course of hospital care. The objective was to characterize the profile of the patients, mortality and factors associated with mortality while in the ICU at the dawn of commencement of neurosurgical services at our centre. A descriptive retrospective study utilizing patients’ datasets of all neurosurgical admissions into the ICU of a tertiary hospital, University of Abuja Teaching Hospital, Abuja, between 2013 and 2015 were analyzed for deaths and factors associated to death. During the 3-years period, 19 neurosurgical deaths occurred in the ICU of University of Abuja Teaching Hospital, translating to a mortality of 63.3%. The majority of the deceased patients (n=22, 71%), was of the young age group and died from head trauma. 14 (73.7%) presented late to the hospital, and all the deceased presented late to the ICU. 17 (89.5%) had head injury, of which, 84.2% was from severe head injury. All the deceased who were administered mannitol died. The early data suggest an unusually high mortality among neurosurgical patients managed in the ICU. A reflected application of modern intensive care measures might lead to increased survival of neurocritically ill patients.

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Citations

Cohen A, Bodenham A, Webster N. A review of 2000 consecutive ICU admissions. Anaesthesia 1993;48:106-10. DOI: https://doi.org/10.1111/j.1365-2044.1993.tb06845.x
Dobb GJ. Pediatric Intensive Care (editorial) Int. Care World 1993;10:165.
Arunodaya GR. Infections in neurology and neurosurgery in Intensive Care Units. Neurol India 2001;49:551-9.
Tweedie I. Neuro-critical care versus general critical care for neurological injury: Beneficial evidence. J Neuroanaesthesiol Crit Care 2016;3:62-5. DOI: https://doi.org/10.4103/2348-0548.174739
Suarez JI, Zaidat OO, Suri MF, et al. Length of stay and mortality in neurocritically ill patients: impact of a specialized neurocritical care team. Critical Care Med 2004;32:2311–7. DOI: https://doi.org/10.1097/01.CCM.0000146132.29042.4C
Varelas PN, Eastwood D, Yun HJ, et al. Impact of a neurointensivist on outcomes in patients with head trauma treated in a neurosciences intensive care unit. J Neurosurg 2006;104:713–9. DOI: https://doi.org/10.3171/jns.2006.104.5.713
Adudu OP, Ogunrin OA, Adudu OG. Morbidity and mortality patterns among neurological patients in the intensive care unit of a tertiary health facility. Ann Afr Med 2007;6:174-9. DOI: https://doi.org/10.4103/1596-3519.55701
Oommen A. Neuro Critical Care - How it makes a Difference in Neurology. J Neurol Stroke 2015;2:00045. DOI: https://doi.org/10.15406/jnsk.2015.02.00045
Greenberg MS. Head trauma. In: Greenberg MS, editor. Handbook of Neurosurgery. New York: Thieme; 2010. p. 850-928.
Schreiber MA, Aoki N, Scott BG, Beck JR. Determinants of mortality in patients with severe blunt head injury. Arch Surg 2002;137:285-90. DOI: https://doi.org/10.1001/archsurg.137.3.285
Clayton TJ, Nelson RJ, Manara AR. Reduction in mortality from severe head injury following introduction of a protocol for intensive care management. Br J Anaesth 2004;93:761–7. DOI: https://doi.org/10.1093/bja/aeh249
Hardman JM, Manoukian A. Pathology of head trauma. Neuroimaging Clin N Am 2002;12:175–87. DOI: https://doi.org/10.1016/S1052-5149(02)00009-6
Wakai A, McCabe A, Roberts I, et al. Mannitol for acute traumatic brain injury. Cochrane Database Syst Rev 2013;2013:CD001049. DOI: https://doi.org/10.1002/14651858.CD001049.pub5
Tobi KU, Azeez AL, Agbedia SO. Outcome of traumatic brain injury in the intensive care unit: a five-year review. S Afr J Anaesth Analg 2016;22:135-9. DOI: https://doi.org/10.1080/22201181.2016.1206293
Song SY, Lee SK, Eom KS, KNTDB Investigators. Analysis of Mortality and Epidemiology in 2617 Cases of Traumatic Brain Injury: Korean Neuro-Trauma Data Bank System 2010-2014. J Korean Neurosurg Soc 2016;59:485-91. DOI: https://doi.org/10.3340/jkns.2016.59.5.485
Donkin JJ, Vink R. Mechanisms of cerebral edema in traumatic brain injury: therapeutic developments. Curr Opin Neurol 2010;23:293-9. DOI: https://doi.org/10.1097/WCO.0b013e328337f451
Opondo EA, Mwangombe NJM. Outcome of severe traumatic brain injury at a critical care unit: a review of 87 patients. Ann Afr Surg 2004;1:1–5.
Gupta D, Sharma D, Kannan N, et al. Guideline Adherence and Outcomes in Severe Adult Traumatic Brain Injury for the CHIRAG (Collaborative Head Injury and Guidelines) Study. World Neurosurg 2016;89:169-79. DOI: https://doi.org/10.1016/j.wneu.2015.12.097
Stocchetti N, Carbonara M, Citerio G, et al. Severe traumatic brain injury: targeted management in the intensive care unit. Lancet Neurol 2017;16:452-64. DOI: https://doi.org/10.1016/S1474-4422(17)30118-7

How to Cite

Obande, J., Otorkpa, E., & Obande, E. (2021). Outcome of management of neurosurgical patients in the intensive care unit: An early clinical audit of a single institution from a developing country. Annals of Clinical and Biomedical Research, 2(1). https://doi.org/10.4081/acbr.2021.89