Knowledge of hepatitis B virus infection and vaccination status among college of medicine students in Enugu State, south-east, Nigeria

Submitted: 11 June 2020
Accepted: 18 September 2020
Published: 21 October 2020
Abstract Views: 948
PDF: 296
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Background: College of Medicine students are at high risk of contracting hepatitis B since they come in contact with infected patients during their training program and are expected to have proper knowledge of the hepatitis B virus infection and know their vaccination status.

The aim of the work: To determine the level of knowledge of hepatitis B virus and the vaccination status among college of medicine students in Enugu State, South-East Nigeria. Methods: A school-based descriptive cross-sectional study was carried among college of medicine students at ESUT College of Medicine, Enugu State. A pretested self-administered questionnaire was used to collect information from 437 students. Data analysis was carried out using the Statistical Package for Social Sciences version (SPSS) 22 and a p-value of 0.05 was used to determine statistical significance.

Results: The mean age of the respondents was 22.3 ± 3.7 years and the majority were single (91.1%) and female (54.7%). A high proportion (68.2%) of the students had a good knowledge of HBV while a minority (20.0%) were aware of their vaccination status. Lack of vaccination programs for students (36.6%) and poor awareness of HBV vaccine for adults (32.5%) were the commoner reasons for non-vaccination. While final year students, (95% CI=1.73-28.92), respondents who consume herbal concussions (95% CI= 0.98-2.96) and those who were at least 30 years old (95% CI=0.32-5.16) were 7.1, 1.7 and 1.3 times respectively more likely to have good knowledge of HBV disease, females (95% CI=0.30-0.83) and respondents who consumed alcohol (95% CI= 0.32-0.89) were about twice less likely to have poor knowledge of HBV than males and non-alcohol consumers.

Conclusion: Although most of the students had a good knowledge of HBV infection their vaccination status was low indicating the need for government to make a policy that would mandate that all college of medicine students should get vaccinated as part of the admission process.

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Citations

Doo EC, Ghany MG. Hepatitis B virology for clinicians. Med Clin North Am 2010;14:397-408.
Aniaku JK, Amedonu EK, Fusheni A. Assessment of knowledge, Attitude and vaccination Status of Hepatitis B among Nursing Training Students in Ho, Ghana. Ann Glob Health 2019;85:18. DOI: https://doi.org/10.5334/aogh.750
National HIV/AIDS and STI Control Program. National Policy for the Control of Viral Hepatitis in Nigeria. 1st ed. Abuja, Nigeria. FMOH 2015;12-14.
Abdul-Hakeem OA, Adebukola BO, Kabir BB, et al. Prevalence of HBsAg, Knowledge and vaccination practice against viral hepatitis B infection among doctors and nurses in a secondary healthcare facility in Lagos state, South-western Nigeria. Pan Afri J 2016;23:160.
Zanetti AR, Van Damme P, Shouval D. The global impact of vaccination against hepatitis B: a historical overview. 2008;26: 6266-73. DOI: https://doi.org/10.1016/j.vaccine.2008.09.056
Perz JF, Armstrong GL, Farvington LA. The contributions of hepatitis B virus and hepatitis C virus infection to cirrhosis and primary liver cancer worldwide. J Hepatol 2006;45:529-38. DOI: https://doi.org/10.1016/j.jhep.2006.05.013
Kramvis A, Kew MC. Epidemiology of hepatitis B virus in Africa, its genotypes and clinical associations of genotypes. Hepatol Res 2007;37:9-19. DOI: https://doi.org/10.1111/j.1872-034X.2007.00098.x
Lemoine M, Eholie S, Lacombe K. Reducing the neglected burden of viral hepatitis in Africa: strategies for a global approach. J Heptol 2015;62:469-76. DOI: https://doi.org/10.1016/j.jhep.2014.10.008
Hepatitis B foundation. The Journey to Hepatitis Elimination in Nigeria. Available from www.hepb.org/blog/journey-hepatitis-elimination-nigeria/. Accessed 25/7/2020.
Odusanya OO, Maurice FB, Hoet B. Nigerian medical students are at risk for hepatitis B infection. Transaction of the Royal Society of Tropical Medicine and Hygiene. 2007;101:465-8. DOI: https://doi.org/10.1016/j.trstmh.2006.08.001
Ibrahim N, Idris A. Hepatitis B awareness among medical students and their vaccination status at Syrian Private University. Hepat Res Treat 2014; 2014:131920. DOI: https://doi.org/10.1155/2014/131920
Nagandia K, Kumar K, Bhardwaj A et al. Prevalence of needlestick injuries and their underreporting among healthcare workers in the dept of obst. and gynae. Int Arch Med 2015;8:1-16.
Chouhon S. Hepatitis B Prophylaxis practice among medical students: An overview. Hep B Annu 2008;5:102-16 DOI: https://doi.org/10.4103/0972-9747.58809
Rachiotis G, Goritsas C, Alikakou V, et al. Vaccination against hepatitis B virus in workers of a general hospital in Athens. Med Lav 2005;96:80-6.
Molinari J. Infection Control: Its evolution to the current standard precautions. J Am Dent Assoc 2003;134:569-74. DOI: https://doi.org/10.14219/jada.archive.2003.0222
Centers for Disease Control and Prevention, Immunization of Adolescents: Recommendation of the Advisory Committee on Immunization Practices, the American Academy of Pediatrics, American Family Physicians and American Medical Association. MMWR. 1996;45:1-14.
Nsirimobu IP, Oliemen P. Hepatitis B vaccination rate among medical students at the University of Port Harcourt Teaching Hospital, River State. Nigerian Health J 2014;14:64-70.
Muhammad SM, Shoaib A, Rashid N, et al. Hepatitis B vaccination status of healthcare worker of two university hospitals. J Liaquat University Med Health Sci 2007;6:48-51. DOI: https://doi.org/10.22442/jlumhs.07610115
World Health Organization & Stop TB Partnership. Advocacy, communication and social mobilization for TB control: a guide to developing knowledge, attitude and practice surveys. World Health Organization, 2008. Available from: http://apps.who.int/iris/handle/10665/43790.
Trepo C. A Brief history of hepatitis milestones. Liver Int 2014;34:29-37. DOI: https://doi.org/10.1111/liv.12409
Ikoba J, Okpara H, Elemi I, et al. The Prevalence of hepatitis B virus Infection in Nigerian children prior to vaccine introduction into the National Programme on Immunization schedule. PAMJ 2016;23:128.
Sadoh A, Nwaneri D, Ogboghodo BC, Sadoh WE. Effects of Introduction of pentavalent vaccine as replacement for Diphtheria-Tetanus and Hepatitis B vaccines on vaccination uptake in a health facility in Nigeria. Vaccine 2016;34:2722-2728. doi: 10.1016/j.vaccine.2016.04.026. DOI: https://doi.org/10.1016/j.vaccine.2016.04.026
Othman SA, Saleh AM, Shabila NP. Knowledge About Hepatitis B Infection among medical students in Erbil City, Iraq. Eur Sci J 2013;3:299-305.
ESUCOM: Induction Ceremony of her 8th batch of Medical Graduands by the Medical and Dental Council of Nigeria, Enugu, Nigeria; 2019.
Isa MA, Bello HS, Mustapha A, et al. Prevalence of hepatitis B Virus among students attending University of Maiduguri clinic, Borno, Nigeria. Int J Adv Res Biol Sci 2015;2:138-42.
Araoye MO. Research methodology with statistics for health and social sciences 1st ed. Nathadex publishers Ilorin, 2004:25-120.
Hassan M, Awosan KJ, Nasir S, et al. Knowledge, risk perception and hepatitis B vaccination status of healthcare workers in Usman Danfodio University Teaching Hospital, Sokoto, Nigeria. J Public Health Epidemiol 2016;8:53-9. DOI: https://doi.org/10.5897/JPHE2015.0795
Velvzhi G, Senthil K, Sucilathangam G, Revathy C. Knowledge and attitude of medical students towards hepatitis B infection. Int J Curr Microbiol App Sci 2016;5:570-6. DOI: https://doi.org/10.20546/ijcmas.2016.506.061
Arun J, Teena MJ, Sreelakshmi M, et al. Assessment of knowledge, attitude, and practice regarding hepatitis B among medical students in a private medical college in Kochi. Int J Community Med Public Health 2019;6:1-5.
Singh A, Jain S. Prevention of Hepatitis B; knowledge and practices among medical students. Healthline 2011;2:8-11.
Baig VN, Gupta PK, Swarnkar M. Assessment of Knowledge, Attitude and practice about hepatitis B among clinicians and medical students: a cross sectional study. Ntl J Community Med 2015;6:415-22.
Al-Hazimi AH. Knowledge, attitude and practice of medical students regarding occupational risks of hepatitis B virus in College of Medicine, Aljouf University. Ann Med Health Sci Res 2015;5:13-9. DOI: https://doi.org/10.4103/2141-9248.149765
Abhinav A, Jeffin JES, Shankar K. Assessment of knowledge, attitude and practice about Hepatitis B and medical students in an urban area of Kanchipuram: A cross sectional study. IAIM 2018;5:17-22.
Omotowo IB, Meka IA, Ijoma UN, et al. Uptake of hepatitis B vaccination and its determinants among health care workers in a tertiary facility in Enugu, South East, Nigeria. BMC Infect Dis 2018;18:288. DOI: https://doi.org/10.1186/s12879-018-3191-9
Okeke E, Ladep N, Agaba E, Malu AO. Hepatitis B vaccination status and needle stick injuries among medical students in a Nigerian university. Nigerian J Med 2008;17:330-2. DOI: https://doi.org/10.4314/njm.v17i3.37404
Adenlewo OJ, Adeosun PO, Fatusi OA. Medical and dental students’ attitude and practice of prevention strategies against hepatitis B virus infection in a Nigerian university. Pan Afr Med J 2017;28:33. DOI: https://doi.org/10.11604/pamj.2017.28.33.11662
Nasir K, Khan KA, Kadri WA, et al. Hepatitis B vaccination among healthcare workers and students of a medical college. J Pak Med Assoc 2000;50:239-43.
Smith DR, Leggat PA. Needle stick and sharp injuries among nursing students. J Adv Nursing 2005;51:449-55. DOI: https://doi.org/10.1111/j.1365-2648.2005.03526.x
Deisehammer S, Radon K, Nowak D, Reichert J. Needlestick injuries medical training. J Hosp Infect 2006;63:263-7. DOI: https://doi.org/10.1016/j.jhin.2006.01.019
Khan D, Shakeel HA, Maqsood H, et al. Immunization status of students of Nishtar medical university against hepatitis B. Int J Res Med Sci 2018;6:3669-72. DOI: https://doi.org/10.18203/2320-6012.ijrms20184427
Ahmed A, Munn S, Rahman H. Factors associated with knowledge, attitude and practice related to hepatitis B and C among international students of Universiti Putra Malaysia. BMC Public Health 2016;6:611. DOI: https://doi.org/10.1186/s12889-016-3188-5
Onyinye Chime, 2Enugu State University Teaching Hospital, Parklane Enugu; 3Enugu State College of Medicine, Nigeria

Hospital Consultant and University Lecturer

Ijeoma Ngozi Nwoke, Enugu State University Teaching Hospital, Parklane Enugu

Department of Community Medicine, Registrar

Anselem Madu, Enugu State University Teaching Hospital, Parklane Enugu

Department of Community Medicine, Registrar

Tonna Aneke, Enugu State University Teaching Hospital, Parklane Enugu

Department of Community Medicine and Registrar

How to Cite

Orji, C., Chime, O., Nwoke, I. N., Madu, A., & Aneke, T. (2020). Knowledge of hepatitis B virus infection and vaccination status among college of medicine students in Enugu State, south-east, Nigeria. Annals of Clinical and Biomedical Research, 1(1). https://doi.org/10.4081/acbr.2020.90