https://doi.org/10.4081/pjm.2022.211

Prevalence and reasons associated with antibiotics misuse and self-medication among adults in Nigeria: A systematic review and meta-analysis [Protocol]

Vol. 5 No. 1 (2022)
Submitted: 21 May 2022
Accepted: 2 June 2022
Published: 28 June 2022
Antibiotics misuse, self-medication, systematic reviews and meta-analysis, Nigeria
Abstract Views: 970
PDF: 205
Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

Authors

  • Yusuf Abdu Misau • amyusuf@atbu.edu.ng Department of Community Medicine College of Medical Sciences, Abubakar Tafawa Balewa University, Nigeria; Department of Epidemiology and Biostatistics, School of Public Health, Mount Kenya University, Thika, Kenya.
  • Dominic Mogere 2Department of Epidemiology and Biostatistics, School of Public Health, Mount Kenya University, Thika, Kenya.
  • Suleiman Mbaruk Department of Epidemiology and Biostatistics, School of Public Health, Mount Kenya University, Thika, Kenya.
  • Segun Bello Department of Epidemiology and Medical Statistics, Faculty of Public Health, College of Medicine, University of Ibadan, Nigeria.
  • Olabisi Oduwole Department of Medical Laboratory Science, College of Basic Health Sciences, Achievers University, Owo, Nigeria.

There is consistent increase in prevalence of antibiotics misuse and self-medication in Nigeria. The exact quality of information available in the public domain is unknown. There is no previous systematic review and meta-analysis that address antibiotics misuse and self-medication in Nigeria. Being the most populous country in Africa, understanding the drivers of antibiotics misuse and self-medication will impact in not only Nigeria, but Africa as a whole. The aim of this systematic review and meta-analysis is therefore to determine the prevalence and factors associated with antibiotics misuse and self-medication among adults in Nigeria. Attempt will be made to find and include published papers on prevalence and reasons associated with antibiotics misuse and self-medication among adults in Nigeria from 2011-2021. Systematic search for the literature will be conducted according to the Preferred Reporting Item for Systematic Reviews and Meta-Analysis (PRISMA) guidelines to identified published studies based on our predetermined inclusion and exclusion criteria in PubMed, EMBASE, PsychINFO, CINAHL and Web of Sciences. Two independent reviewers will assess all identified studies and another set of reviewers will extract data for analysis and evidence synthesis.

Dimensions

Altmetric

PlumX Metrics

Downloads

Download data is not yet available.

Citations

Crossref
Scopus
Google Scholar
Europe PMC
Nepal G, Bhatta S. Self-medication with Antibiotics in WHO Southeast Asian Region: A Systematic Review. Cureus 2018;10:e2428. DOI: https://doi.org/10.7759/cureus.2428
Chen J, Sidibi AM, Shen X, et al. Lack of antibiotic knowledge and misuse of antibiotics by medical students in Mali: a cross-sectional study. Expert Rev Anti Infect Ther 2021;19:797-804. DOI: https://doi.org/10.1080/14787210.2021.1857731
Misau YA, Mohammed A, Jibrin YB, et al. Antibiotics self-medication among medical students in a new medical college at Abubakar Tafawa Balewa university Bauchi, Nigeria. Pyramid J Med 2020;2:25. DOI: https://doi.org/10.4081/pjm.2019.25
Chem ED, Anong DN, Akoachere JFKT. Prescribing patterns and associated factors of antibiotic prescription in primary health care facilities of Kumbo east and Kumbo west health districts, northwest Cameroon. PLoS one 2018;13:e0193353. DOI: https://doi.org/10.1371/journal.pone.0193353
Vazquez-Cancela O, Souto-Lopez L, Vazquez-Lago JM, et al. Factors determining antibiotic use in the general population: A qualitative study in Spain. PLoS One 2021;16:e0246506. DOI: https://doi.org/10.1371/journal.pone.0246506
Abdi A, Faraji A, Dehghan F, Khatony A. Prevalence of self-medication practice among health sciences students. BMC Pharmacol Toxicol 2018;19:36. DOI: https://doi.org/10.1186/s40360-018-0231-4
Jamhour A, El-Kheir A, Salameh P, et al. Antibiotic knowledge and self-medication practices in a developing country: A cross-sectional study. Am J Infect Control 2017;45:384-8. DOI: https://doi.org/10.1016/j.ajic.2016.11.026
Limaye D, Limaye V, Krause G, Fortwengel G. A systematic review of the literature to assess self- medication practices. Ann Med Health Sci Res 2017;7:1-15 DOI: https://doi.org/10.18203/2394-6040.ijcmph20173192
Akande-Sholabi W, Ajamu AT, Adisa R. Prevalence, knowledge and perception of self-medication practice among undergraduate healthcare students. J Pharmaceut Policy Pract 2021;14:1–11. DOI: https://doi.org/10.1186/s40545-021-00331-w
Babatunde OA, Fadare JO, Ojo OJ, et al. Self-medication among health workers in a tertiary institution in south-west Nigeria. Pan Afr Med J 2016;24:1–8.
Chang FR, Trivedi PK. Economics of self-medication: theory and evidence. Health Econ 2003;12:721-39. DOI: https://doi.org/10.1002/hec.841
Malik B, Bhattacharyya S. Antibiotic drug-resistance as a complex system driven by socio-economic growth and antibiotic misuse. Sci Rep 2019;9:9788. DOI: https://doi.org/10.1038/s41598-019-46078-y
Torres NF, Solomon VP, Middleton LE. Patterns of self-medication with antibiotics in Maputo city: A qualitative study. Antimicrob Res Infect Control 2019;8:161. DOI: https://doi.org/10.1186/s13756-019-0618-z
Ruiz ME. Risks of self-medication practices. Curr Drug Saf 2010;5:315-23. DOI: https://doi.org/10.2174/157488610792245966
Leung E, Weil DE, Raviglione M, et al. The WHO policy package to combat antimicrobial resistance. Bull World Health Organ 2011;89:390-2. DOI: https://doi.org/10.2471/BLT.11.088435
Hadi U, Duerink DO, Lestari ES, et al. Survey of antibiotic use of individuals visiting public healthcare facilities in Indonesia. Int J Infect Dis 2008;12:622-9. DOI: https://doi.org/10.1016/j.ijid.2008.01.002
Helal RM, Abou-ElWafa HS. Self-Medication in University Students from the City of Mansoura, Egypt. J Environ Public Health 2017;2017:9145193. DOI: https://doi.org/10.1155/2017/9145193
Osemene KP, Lamikanra A. A study of the prevalence of self-medication practice among university students in southwestern Nigeria. Trop J Pharmaceut Res 2012;11:683-9. DOI: https://doi.org/10.4314/tjpr.v11i4.21
Linnenluecke MK, Marrone M, Singh AK. Conducting systematic literature reviews and bibliometric analyses. Austral J Manag 2020;45:175–94. DOI: https://doi.org/10.1177/0312896219877678
Yeika EV, Ingelbeen B, Kemah BL, et al. Comparative assessment of the prevalence, practices and factors associated with self-medication with antibiotics in Africa. Trop Med Int Health 2021;26:862-81. DOI: https://doi.org/10.1111/tmi.13600
Worldmeter. Nigeria population. 2022. Available from: https://www.worldometers.info/world-population/nigeria-population/
Levett P. Systematic Reviews: Medical Literature Databases to search. Himmelfarb Health Sciences Library. Available from: https://guides.himmelfarb.gwu.edu/systematic_review/medical-literature-databases-to-search
Goossen K, Hess S, Lunny C, Pieper D. Database combinations to retrieve systematic reviews in overviews of reviews: a methodological study. BMC Med Res Methodol 2020;20:138. DOI: https://doi.org/10.1186/s12874-020-00983-3
Migliavaca CB, Stein C, Colpani V, et al. How are systematic reviews of prevalence conducted: A methodological study. BMC Med Res Methodol 2020;20:96. DOI: https://doi.org/10.21203/rs.2.20036/v1
Hoy D, Brooks P, Woolf A, et al. Assessing risk of bias in prevalence studies: modification of an existing tool and evidence of interrater agreement. J Clin Epidemiol 2012;65:934-9. DOI: https://doi.org/10.1016/j.jclinepi.2011.11.014
Lin L, Xu C. Arcsine-based transformations for meta-analysis of proportions: Pros, cons, and alternatives. Health Sci Rep 2020;3:e178. DOI: https://doi.org/10.1002/hsr2.178
Barendregt JJ, Doi SA, Lee YY, et al. Meta-analysis of prevalence. J Epidemiol Community Health 2013;67:974-8. DOI: https://doi.org/10.1136/jech-2013-203104
Ma LL, Wang YY, Yang ZH, et al. Methodological quality (risk of bias) assessment tools for primary and secondary medical studies: what are they and which is better? Military Med Res 2020;7:7. DOI: https://doi.org/10.1186/s40779-020-00238-8
Lo CK, Mertz D, Loeb M. Newcastle-Ottawa Scale: comparing reviewers' to authors' assessments. BMC Med Res Methodol 2014;14:45. DOI: https://doi.org/10.1186/1471-2288-14-45

How to Cite

Misau, Yusuf Abdu, Dominic Mogere, Suleiman Mbaruk, Segun Bello, and Olabisi Oduwole. 2022. “Prevalence and Reasons Associated With Antibiotics Misuse and Self-Medication Among Adults in Nigeria: A Systematic Review and Meta-Analysis [Protocol]”. Pyramid Journal of Medicine 5 (1). https://doi.org/10.4081/pjm.2022.211.

PAGEPress has chosen to apply the Creative Commons Attribution NonCommercial 4.0 International License (CC BY-NC 4.0) to all manuscripts to be published.