Sensitivity of electroencephalogram in the diagnosis of epilepsy among patients attending a neuropsychiatric hospital in Northern Nigeria

Submitted: 5 March 2020
Accepted: 12 April 2020
Published: 7 September 2020
Abstract Views: 349
PDF: 192
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Electroencephalography (EEG) is an essential adjunct in management of epilepsy. While some studies reported that EEG has a high sensitivity in detecting epileptic seizures, others disagree. Therefore, it is important to know sensitivity of this important procedure in our setting. This was a cross-sectional study carried out from 2015 to 2018. Participants were patients attending the outpatient clinic of a psychiatric hospital to achieve care for epileptic seizures. Ethical clearance was obtained prior to the conduct of this study. In addition, informed consent was obtained from each patient or their caregivers. Data analysis was done using SPSS version 20. The study involved 177 participants aged 2-70 years (median = 17 years). The male to female ratio was 2:1. The mean duration of illness was 7.8±5.8 (range = 1-35 years). Sensitivity of EEG was 70.6%. There was no difference between either age, gender or duration of illness and probability of having an abnormal EEG. EEG is sensitive in the diagnosis of epilepsy in our setting. Future studies should focus on factors influencing sensitivity of EEG in diagnosis of epilepsy.

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Citations

Epilepsy [Internet]. [cited 2020 Feb 23]. Available from: https://www.who.int/news-room/fact-sheets/detail/epilepsy
Tudor M, Tudor L, Tudor KI. [Hans Berger (1873-1941)--the history of electroencephalography]. Acta Med Croatica [Internet]. 2005 [cited 2020 Feb 23];59:307–13. Available from: http://www.ncbi.nlm.nih.gov/pubmed/16334737
Gururangan K, Razavi B, Parvizi J. Diagnostic utility of eight-channel EEG for detecting generalized or hemispheric seizures and rhythmic periodic patterns. Clin Neurophysiol Pract. 2018;3:65–73. DOI: https://doi.org/10.1016/j.cnp.2018.03.001
Suarez-Revelo J, Ochoa-Gomez J, Duque-Grajales J. Improving test-retest reliability of quantitative electroencephalography using different preprocessing approaches. In: Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS. Institute of Electrical and Electronics Engineers Inc.; 2016. p. 961–4. DOI: https://doi.org/10.1109/EMBC.2016.7590861
Paliwal P, Wakerley BR, Yeo LLL, et al. Early electroencephalography in patients with Emergency Room diagnoses of suspected new-onset seizures: Diagnostic yield and impact on clinical decision-making. Seizure. 2015;31:22–6. DOI: https://doi.org/10.1016/j.seizure.2015.06.013
Owolabi L, Owolabi S, Shehu S, Umar M. Interictal electroencephalography in patients with epilepsy in northwestern Nigeria. Ann Niger Med [Internet]. 2013 [cited 2020 Feb 18];7:48. Available from: http://www.anmjournal.com/text.asp?2013/7/2/48/133096 DOI: https://doi.org/10.4103/0331-3131.133096
Tu B, Young GB, Kokoszka A, et al. Diagnostic accuracy between readers for identifying electrographic seizures in critically ill adults. Epilepsia Open. 2017;2:67–75. DOI: https://doi.org/10.1002/epi4.12034
Chowdhury AH, Chowdhury RN, Khan SU, et al. Sensitivity and Specificity of Electroencephalography (EEG) Among Patients Referred to an Electrophysiology Lab in Bangladesh. J Dhaka Med Coll. 2015;23:215–22. DOI: https://doi.org/10.3329/jdmc.v23i2.25394
MacDonald DB. Electroencephalography: Basic Principles and Applications. In: International Encyclopedia of the Social & Behavioral Sciences: Second Edition. Elsevier Inc.; 2015. p. 353–63. DOI: https://doi.org/10.1016/B978-0-08-097086-8.55017-X
Tripathi M, Mehendiratta MM. Role of EEG in Epilepsy. In: Epilepsy Topics. InTech; 2014. DOI: https://doi.org/10.5772/57430
Igwe SC, Brigo F, Beida O. Patterns of diagnosis and therapeutic care of epilepsy at a tertiary referral center in Nigeria. Epilepsia. 2014;55:442–7. DOI: https://doi.org/10.1111/epi.12531
Bouma HK, Labos C, Gore GC, et al. The diagnostic accuracy of routine electroencephalography after a first unprovoked seizure. Vol. 23, European Journal of Neurology. Blackwell Publishing Ltd; 2016. p. 455–63.
Chen DK, Graber KD, Anderson CT, Fisher RS. Sensitivity and specificity of video alone versus electroencephalography alone for the diagnosis of partial seizures. Epilepsy Behav. 2008;13:115–8. DOI: https://doi.org/10.1016/j.yebeh.2008.02.018
Geut I, Weenink S, Knottnerus ILH, van Putten MJAM. Detecting interictal discharges in first seizure patients: ambulatory EEG or EEG after sleep deprivation? Seizure. 2017;51:52–4. DOI: https://doi.org/10.1016/j.seizure.2017.07.019
Owolabi LF, Sale S, Owolabi SD, et al. Electroencephalography abnormalities in generalized epilepsy and their predictors: A multicenter experience. Ann Afr Med. 2018;17:64–9. DOI: https://doi.org/10.4103/aam.aam_2_17
Bouma HK, Labos C, Gore GC, et al. The diagnostic accuracy of routine electroencephalography after a first unprovoked seizure [Internet]. Vol. 23, European Journal of Neurology. Blackwell Publishing Ltd; 2016 [cited 2020 Feb 18]. p. 455–63. Available from: http://www.ncbi.nlm.nih.gov/pubmed/26073548 DOI: https://doi.org/10.1111/ene.12739
Watson P, Conroy A, Moran G, Duncan S. Retrospective study of sensitivity and specificity of EEG in the elderly compared with younger age groups. Epilepsy Behav. 2012;25:408–11. DOI: https://doi.org/10.1016/j.yebeh.2012.07.030
Ahammad N, Fathima T, Joseph P. Detection of Epileptic Seizure Event and Onset Using EEG. 2014 [cited 2020 Feb 28]; Available from: http://dx.doi.org/10.1155/2014/450573 DOI: https://doi.org/10.1155/2014/450573
Ajiboye PO, Abiodun OA, Ogbebor AI. An investigation of the patterns and outcomes of electroencephalographic (EEG) recording requests in the management of neuropsychiatric disorders in a teaching hospital in Nigeria. Afr Health Sci. 2017;17:852–8. DOI: https://doi.org/10.4314/ahs.v17i3.28
Olisah V, Adekeye O, Okpataku C, Eseigbe E. Electroencephalographic findings in patients referred for electroencephalogram in a University Teaching Hospital in Northern Nigeria. Sahel Med J. 2015;18:78. DOI: https://doi.org/10.4103/1118-8561.160805
Ogunlesi T, Ogundeyi M, Olowu A. Pattern of childhood epilepsies in Sagumu, Nigeria. Indian J Pediatr. 2009;76:385–9. DOI: https://doi.org/10.1007/s12098-009-0022-4
Trinka E, Ben-Menachem E, Kowacs PA, et al. Efficacy and safety of eslicarbazepine acetate versus controlled-release carbamazepine monotherapy in newly diagnosed epilepsy: A phase III double-blind, randomized, parallel-group, multicenter study. Epilepsia [Internet]. 2018 [cited 2020 Mar 2];59:479–91. Available from: http://doi.wiley.com/10.1111/epi.13993 DOI: https://doi.org/10.1111/epi.13993
Aina OF, Ogun OC, Ladapo HTO, et al. Clinical neuropsychiatric correlates and EEG findings among children with developmental disorders in Lagos, Nigeria. African J Psychiatry (South Africa). 2008;11:123–7. DOI: https://doi.org/10.4314/ajpsy.v11i2.30264
Fields M, Sazgar M, Harden CL. Epilepsy inheritance. In: Controversies in Caring for Women with Epilepsy: Sorting Through the Evidence. Springer International Publishing; 2016. p. 81–6. DOI: https://doi.org/10.1007/978-3-319-29170-3_10
Bianchi A, Viaggi S, Chiossi E,et al. Family study of epilepsy in first degree relatives: Data from the Italian Episcreen study. Seizure. 2003;12:203–10. DOI: https://doi.org/10.1016/S1059-1311(02)00262-5

How to Cite

Sale, Shehu. 2020. “Sensitivity of Electroencephalogram in the Diagnosis of Epilepsy Among Patients Attending a Neuropsychiatric Hospital in Northern Nigeria”. Pyramid Journal of Medicine 3 (1). https://doi.org/10.4081/pjm.2020.79.