https://doi.org/10.4081/aamr.2024.482

Venous thromboembolism among gynecologic cancer patients in Zaria

Vol. 7 (2024)
Submitted: February 3, 2024
Accepted: March 25, 2024
Published: November 11, 2024
Venous Thromboembolism, gynecologic cancers, Deep Venous Thrombosis, Zaria
Abstract Views: 41
PDF: 37
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Authors

Hauwa Sanusi Gumbi
https://orcid.org/0000-0002-1915-8962
Department of Obstetrics and Gynaecology, Ahmadu Bello University Teaching Hospital, Zaria, Nigeria.
Anisah Yahya
https://orcid.org/0000-0003-3908-0047
Department of Obstetrics and Gynaecology, Ahmadu Bello University Teaching Hospital, Zaria, Nigeria.
Musliu Tolani
https://orcid.org/0000-0003-4296-9744
Department of Urology, Ahmadu Bello University Teaching Hospital, Zaria, Nigeria.
Marliyya Zayyan
Department of Obstetrics and Gynaecology, Ahmadu Bello University Teaching Hospital, Zaria, Nigeria.
Aisha Mustapha
aisha.mustapha@npmcn.edu.ng
https://orcid.org/0000-0001-5599-5453
Department of Obstetrics and Gynaecology, Ahmadu Bello University Teaching Hospital, Zaria, Nigeria.
Abimbola Omolara Kolawole
Department of Obstetrics and Gynaecology, Ahmadu Bello University Teaching Hospital, Zaria, Nigeria.
Sunday Adewuyi
Department of Radiotherapy/Oncology, Ahmadu Bello University Teaching Hospital, Zaria, Nigeria.
Adekunle Oguntayo
Department of Obstetrics and Gynaecology, Ahmadu Bello University Teaching Hospital, Zaria, Nigeria.

Cancer is one of the most important acquired risk factors for Venous Thromboembolism (VTE) including Deep Vein Thrombosis (DVT) and Pulmonary Embolism (PE). Patients with active malignancy have up to six-fold increased risk of symptomatic VTE than the general population. The risk of VTE in patients with gynecologic malignancy is especially high because of the nature of the tumor, its pelvic location, associated comorbidities, and systemic chemotherapy.

The objective of this study was to determine other risk factors, incidence, clinical presentation, and immediate outcome of treatment of thromboembolism in patients with gynecologic cancers in Ahmadu Bello University Teaching Hospital (ABUTH), Zaria, Nigeria.

It was a retrospective cross-sectional descriptive study of gynecologic cancer cases that were diagnosed with VTE while on admission from 2007-2016 in ABUTH.

The overall prevalence of clinical VTE was 2.8% in gynaecologic malignancy. All were DVT. Most cases of DVT were present in ovarian cancers with left-sided preponderance.

There is a need for the provision of modern imaging equipment to facilitate timely and highly sensitive diagnosis of VTE in low-resource settings. The main limitation of this study was the inability to find any confirmed case of PE.

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How to Cite

Sanusi Gumbi, H., Yahya, A., Tolani, M., Zayyan, M., Mustapha, A., Kolawole, A. O., … Oguntayo, A. (2024). Venous thromboembolism among gynecologic cancer patients in Zaria. Annals of African Medical Research, 7(1). https://doi.org/10.4081/aamr.2024.482
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