Biochemical pattern and prevalence of thyroid disorders among adults in a tertiary hospital in North-East Nigeria

Submitted: February 10, 2024
Accepted: March 1, 2024
Published: June 3, 2024
Abstract Views: 25
PDF: 21
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Thyroid disorders are a relatively common group of endocrine disorders globally. Thyroid function tests are critical for diagnosing, screening, and prognosticating thyroidal and non-thyroidal diseases, and their accurate interpretation is required for effective and accurate patient management. A retrospective analysis of thyroid function tests - Thyroid Stimulating Hormone (TSH), Free Thyroxine (fT4), and Free Triiodothyronine (fT3) - was carried out at a Nigerian tertiary hospital between January 2017 and January 2024. The tests were conducted using an enzyme-linked fluorescent immunoassay system and interpreted following standard protocols. A preponderance of female patients was investigated for thyroid diseases, with a male-female ratio of 2.2:1. The majority (80.8%) of the analyzed requests showed a euthyroid pattern; primary hyperthyroidism was the most common biochemical pattern of thyroid dysfunction observed, accounting for 10.8% of all the analyzed requests. Secondary hyperthyroidism and hypothyroidism were generally rare. Occasional cases (0.3%) of T3 toxicosis were also observed. Goiters remain a common presentation of thyroid diseases in our environment. Primary hyperthyroidism and primary hypothyroidism are the most common forms of thyroid dysfunction observed.

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How to Cite

Ibrahim Abubkar, B., Saleh, L. A., Suleiman, D. E., Musa, S., Adegoke, B. O., Naziru, I., … Isichei, C. (2024). Biochemical pattern and prevalence of thyroid disorders among adults in a tertiary hospital in North-East Nigeria. Annals of African Medical Research, 7(1). https://doi.org/10.4081/aamr.2024.485