https://doi.org/10.4081/aamr.2024.485

Biochemical pattern and prevalence of thyroid disorders among adults in a tertiary hospital in North-East Nigeria

Vol. 7 (2024)
Submitted: February 10, 2024
Accepted: March 1, 2024
Published: June 3, 2024
TFT, thyroid, dysfunction, North East, Nigeria
Abstract Views: 88
PDF: 69
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Authors

Bawa Ibrahim Abubkar
iabawa@atbu.edu.ng
https://orcid.org/0009-0009-3446-7104
Department of Chemical Pathology, Abubakar Tafawa Balewa University, Bauchi, Nigeria.
Longwap Abdulazis Saleh
Department of Chemical Pathology, University of Jos, Nigeria.
Dauda E. Suleiman
Department of Histopathology, Abubakar Tafawa Balewa University, Bauchi, Nigeria.
Sanni Musa
Department of Chemical Pathology, Kaduna State University, Kaduna, Nigeria.
Bosede Oluwasayo Adegoke
Department of Chemical Pathology, Ekiti State University, Ado-Ekiti, Nigeria.
Ibrahim Naziru
Department of Anesthesia and Critical Care, Gombe State University, Gombe, Nigeria.
Abbas Hamisu
Department of Chemical Pathology, Abubakar Tafawa Balewa University, Bauchi, Nigeria.
Harisu Salisu
Department of Chemical Pathology, Abubakar Tafawa Balewa University, Bauchi, Nigeria.
Rabi’atu Ahmad Bichi
Department of Pathology, Muhammad Abdullahi Wase Teaching Hospital, Kano, Nigeria.
Mansur Ramalan Aliyu
Department of Pharmacology and Therapeutics, Baze University, Abuja, Nigeria.
Christian Isichei
Department of Chemical Pathology, University of Jos, Nigeria.

Thyroid disorders are a relatively common group of endocrine disorders globally. Thyroid function tests are critical for diagnosing, screening, and prognosticating thyroidal and non-thyroidal diseases, and their accurate interpretation is required for effective and accurate patient management. A retrospective analysis of thyroid function tests - Thyroid Stimulating Hormone (TSH), Free Thyroxine (fT4), and Free Triiodothyronine (fT3) - was carried out at a Nigerian tertiary hospital between January 2017 and January 2024. The tests were conducted using an enzyme-linked fluorescent immunoassay system and interpreted following standard protocols. A preponderance of female patients was investigated for thyroid diseases, with a male-female ratio of 2.2:1. The majority (80.8%) of the analyzed requests showed a euthyroid pattern; primary hyperthyroidism was the most common biochemical pattern of thyroid dysfunction observed, accounting for 10.8% of all the analyzed requests. Secondary hyperthyroidism and hypothyroidism were generally rare. Occasional cases (0.3%) of T3 toxicosis were also observed. Goiters remain a common presentation of thyroid diseases in our environment. Primary hyperthyroidism and primary hypothyroidism are the most common forms of thyroid dysfunction observed.

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How to Cite

Ibrahim Abubkar, B., Saleh, L. A., Suleiman, D. E., Musa, S., Adegoke, B. O., Naziru, I., … Isichei, C. (2024). Biochemical pattern and prevalence of thyroid disorders among adults in a tertiary hospital in North-East Nigeria. Annals of African Medical Research, 7(1). https://doi.org/10.4081/aamr.2024.485
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