Effect of topical bupivacaine on post-tonsillectomy pain relief in children

Submitted: 8 September 2019
Accepted: 27 October 2019
Published: 23 February 2021
Abstract Views: 332
PDF: 205
Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

Authors

Tonsillectomy is a common surgery performed in paediatric otorhinolaryngology and is usually accompanied by considerable postoperative pain. Earlier literature has shown the use of topical bupivacaine for post-tonsillectomy pain relief to be promising. This study was conducted to evaluate the efficacy of topical bupivacaine application on post-tonsillectomy pain relief. Fifty consenting patients scheduled for tonsillectomy that met the inclusion criteria were enrolled in the study and assigned into two groups of 25 patients each. Group B had their tonsillar fossa packed with 0.5% bupivacaine soaked gauze for 5 minutes while Group S had normal saline. Pain intensity was measured at 1, 2, 4, 12 and 24 hours postoperatively, using the Faces Pain Scale- Revised (FPS-R). Mean scores for groups B and S at 1, 2, 4, 8, 12, 24 hours were 1.96±1.17, 2.40±0.82, 2.8±1.0, 2.88±1.17, 3.08±0.99, and 3.04±1.02 and 3.36±1.38, 4.72±1.62, 3.92±1.35, 3.76±1.45, 4.00±1.41, 3.38±0.98 respectively. The difference was significant at 1 and 2 hours only (P≤0.05). Post-tonsillectomy pain was reduced in the first two hours by application of bupivacaine soaked gauze.

Dimensions

Altmetric

PlumX Metrics

Downloads

Download data is not yet available.

Citations

Mitchell RB, Archer SM, Ishman SL, Rosenfeld RM, Coles S, Finestone SA, et al. Clinical practice guideline: tonsillectomy in children (Update)—Executive summary. Otolaryngol Head Neck Surg. 2019;160:187–205. DOI: https://doi.org/10.1177/0194599818807917
Sabbar S, Khan FA, Khalid A. The Effect of topical bupivacaine 0.5% 0n post-tonsillectomy pain. Med Channel. 2009;15:15–7.
Bameshki AR, Razban M, Khadivi E, Razavi M, Bakhshaee M. The effect of local injection of epinephrine and bupivacaine on post-tonsillectomy pain and bleeding. Iran J Otorhinolaryngol. 2013;25:209–13.
Ehsan-Ul-Haq, Udaipurwala HI, Farrukh MS, Kumar H. Post-tonsillectomy pain reduction by application of bupivacaine pack in the tonsillar fossa. Pak J Surg. 2009;25:76–9.
Hydri AS, Malik SM. Post-tonsillectomy pain and bupivacaine: An intra-individual design study. J Coll Physicians Surg Pak. 2010;20:538–41.
Ellis P. Visual loss following tonsillectomy: Possible association with injections in tonsillar fossae. Arch Otolaryngol. 1968;87:128–30. DOI: https://doi.org/10.1001/archotol.1968.00760060438020
Cyna A, Bell K, Flood L. Cervical osteomyelitis following tonsillectomy. Anaesth. 1997;52:1084–7. DOI: https://doi.org/10.1111/j.1365-2044.1997.215-az0356.x
Bean-Lijewski JD. Glossopharyngeal nerve block for pain relief after pediatric tonsillectomy: Retrospective analysis and two cases of life-threatening upper airway obstruction from an interrupted trial. Anesth Analg. 1997;84:1232–8. DOI: https://doi.org/10.1213/00000539-199706000-00011
Sharma S, Dave V, Zalawadia B, Shah S. The effect of topical bupivacaine in post-tonsillectomy pain relief. GCSMC J Med Sci. 2015;4:15–8.
Hydri AS, Nawaid MA, Afridi JA. Comparison of local application versus infiltration of bupivacaine for post-tonsillectomy pain in adults. Ann Pak Inst Med Sci. 2012;8:3–5.
Kelly LE, Sommer DD, Ramakrishna J, Hoffbauer S, Arbab-tafti S, Reid D, et al. Morphine or Ibuprofen for post-tonsillectomy analgesia: A randomized trial. Pediatr. 2015;135:307–13. DOI: https://doi.org/10.1542/peds.2014-1906
Lewis SR, Nicholson A, Cardwell ME, Siviter G, Smith AF. Nonsteroidal anti-inflammatory drugs and perioperative bleeding in paediatric tonsillectomy. Cochrane database Syst Rev. 2013;(7):CD003591. DOI: https://doi.org/10.1002/14651858.CD003591.pub3
Feroz S, Mahmood Z, Khatri F, Alam J, Abbas M. Can post-tonsillectomy pain be reduced by topical bupivacaine ? A prospective randomized trial. Pak J Otolaryngol. 2013;29:11–5.
Kouchi M, Mochimaru M, Tsuzuki K, Yokoi T. Interobserver errors in anthropometry. J Hum Ergol (Tokyo). 1999;28:15–24.
Khan MI, Shah SF, Muhammad, Iqbal K, Khan IM, Shah SF, et al. Relief of post-tonsillectomy pain by topical application of bupivacaine. Khyber Med Univ J. 2012;4:183–6.
Saki N, Jasemi NA, Mashali L, Baikpour M, Nikakhlagh S, Abshirini H. Effect of topical bupivacaine on post-tonsillectomy pain relief in children. Jundishapur J Nat Pharm Prod. 2015;10:1–3.

How to Cite

Suleiman, Musa Kallamu, Abdulkarim Aitek Abdullahi, Alhassan Datti Mohammed, Kufre Robert Iseh, Abdulrahman Aliyu, and Ibrahim Galadima Bello. 2021. “Effect of Topical Bupivacaine on Post-Tonsillectomy Pain Relief in Children”. Pyramid Journal of Medicine 3 (2). https://doi.org/10.4081/pjm.2020.64.